Product Development & Supply
Who are we?
We are one of the world’s leading healthcare companies. GSK researches, develops, manufactures and distributes life-saving vaccines, prescription medicines and consumer health products such as Sensodyne, Aquafresh and Panadol.
The size and scope of our organisation allows our people to answer some of the biggest questions facing everyone on the planet – questions about future healthcare needs.
What’s this area all about?
Product Development & Supply progresses the development of new drug products from discovery through clinical trials and registration to the factory and beyond. We turn the substance with the pharmacological activity into a high quality formulation or device that patients and volunteers in clinical trials can take or use. We are responsible for the design, development and industrialisation of medicines (e.g. tablets, capsules, vials, inhalers and suspensions) that meet the needs of the patient. We manage R&D supply chains to ensure the right experimental medicine or discovery research compound (chemical and biological) get to the right place at the right time to meet the needs of clinical trial volunteers and scientists respectively. Our science, engineering and supply chain activities are critical functions that enable GSK to register and launch three to five new medicines each year.
What roles are available?
This year we are recruiting two engineers and a process chemist.
Applied Mechanical/Biomedical Engineer (Devices)
As an applied mechanical/biomedical engineer (devices) at GSK, you will:
- Contribute to detailed review of different technologies and device designs to identify potential strengths/weaknesses/opportunities/threats
- Build mathematical models using state-of-the-art Computer Aided Engineering tools to understand the operating space, within which a technology and/or device design will operate
- Effectively communicate your observations and design remediation ideas based upon your mathematical models
- Design, develop and execute test protocols to validate your mathematical models and design remediation ideas to guide product development
- Demonstrate an understanding of the literature in your area of technical competency
- Actively communicate promising ideas/technologies
- Develop a working understanding of the product development process so that you can effectively operate in the broader matrix team
- Interact with suppliers, peers and/or formulation scientists to support ongoing projects in order to develop robust, differentiated patient-centric medicines.
If you have, or expect to obtain in 2017, a Masters (2.1 or better) in mechanical engineering, applied mechanical engineering, biomedical engineering, applied physics or a related subject, you would be eligible to apply for this position.
As an automation engineer at GSK, you will:
- Lead the conceptual and detailed design of instrumentation, control, and manufacturing systems including Delta V, Syncade, Allen Bradley SCADA, Honeywell Building Automation System, and utility PLCs
- Interface with users, peers, and management to analyze, derive, and capture requirements. Lead a team of external resources to deliver platform components to meet the requirements and realize business value
- Identify potential improvement projects and support the business case for investment to management
- Define a detailed plan to complete approved projects on schedule and within budget
- Manage vendors and consultants to ensure that contracts meet scope and budget
- Work with other plant operations, engineering, and product introduction teams to implement and maintain automation systems, execute projects and communicate the status effectively
- Develop and optimize operation and maintenance procedures as well as training programs for manufacturing systems
- Support the development of validation documentation and implement validation plans for instrumentation and control systems
- Maintain and document all cGMP equipment/system modifications and upgrades through approved change control methods
- Support on-time completion of quality investigations, corrective actions and preventative actions as required.
In this role, you are the technical expert and leader for all instrumentation and control systems that support the pilot plant operations on site. The role in the R&D supply chain, Core Technologies Automation team, will help drive and lead projects, truly owning them; quickly working out what needs to be done, who needs to be connected, and executing the work with top tier compliance and efficiency. The role will support delivery of the strategy for the reliability, maintenance, performance improvement and compliance of the automation infrastructure for the primary and secondary clinical manufacturing facilities and equipment.
If you have, or expect to obtain in 2017, a Masters (2:1 or better) or PhD in computer science, data analytics, engineering (mechanical, electrical, industrial, or chemical) or a closely related discipline where you used computer programming to solve challenging scientific or technical problems, you would be eligible to apply for this position.
As a process chemist at GSK, you will:
- Play a significant role in the discovery and development of new chemical processes to synthesise drug substances
- Use your skills and knowledge in organic chemistry to design and execute experimental work to support the delivery of new synthetic routes and robust manufacturing processes for novel target molecules
- Carry out laboratory work to high standards of safety and quality and actively communicate results and progress to your team
- Solve complex problems using scientific and technical expertise in order to progress the development of new drug products
- Support technology transfer of manufacturing processes for drug substances to GSK and/or third party sites of manufacture
- Continue to develop and maintain a high level of relevant scientific and technical expertise in the area of synthetic organic chemistry, including developing a detailed understanding of the requirements of late phase product development such as statistical and first principles modelling
- Liaise with key customers in other disciplines across the business in order to deliver product development projects.
If you have, or expect to obtain in 2017, a Bachelors or Masters (2.1 or better) in chemistry, you would be eligible to apply for this position.
What will I learn?
Part of a vibrant, global scientific community, you’ll work in teams that combine a mix of disciplines. You’ll contribute to multidisciplinary teams that deliver consistent quality in drug substance and drug product. You’ll never be far from an expert who can help you to learn, grow and contribute to our business – and you’ll be coached and mentored to become a technical leader of the future.
Where can I work?
Our Product Development & Supply Future Leaders Programme is based at Stevenage, Ware or Harlow (depending on the role).
What’s expected of me?
We’ll expect you to get involved in delivering technical projects and prioritising a variety of tasks effectively in support of the drug product development process. You’ll need to build working relationships with people across the GSK organisation. To be successful you will need to develop highly effective communication and listening skills, new technical capabilities and knowledge.
What do I need to succeed?
The degree requirements depend on the role but you’ll need to be ambitious and self-motivated. You'll need the ability to interpret information and a passion for developing medicines. We’re looking for proactive graduates who can quickly build a rapport with a wide range of people. It’s also important that you can adapt to change and keep focused when the pressure is on. While you have the drive and confidence to trust your own judgement, you’re a real team player who actively collaborates with others. In addition, you’ll need an analytical mind, a talent for multi-tasking and the ability to influence others.
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